English

PUBLICATIONS

Spinal Cord Injuries

Al-Zoubi A, Jamous M, Khabaz MN, Khaledi R, Al Khateeb M, Al-Zoubi Z. Purification of mouse bone marrow-derived stem cells promotes ex vivo neuronal differentiation. Cell Transplant (2010)19(2):193-202
Al-Zoubi A, Jafar E, Jamous M, Al-Twal F, Al-Bakheet S, Zalloum M, Khalifeh F, Radi SA, El-Khateeb M, Al-Zoubi Z. Transplantation of Purified Autologous Leukapheresis-Derived CD34+ and CD133+ Stem Cells for Patients with Chronic Spinal Cord Injuries: Long-term Evaluation of Safety and Efficacy. Cell Transplant. 2014, Nov 4.
Adeeb Al-Zoubi, Mohammad Jamous, Mohammed El-Khateeb, Emad Jafar, Ziad Al-Zoubi. Transplantation of Leukapheresis-Derived Purified Autologous CD34+ and CD133+ Stem Cells for Patients with Complete Spinal Cord Injuries: A novel Method for Preserving the Immune Privilege of The CNS. Submitted for publication.
Adeeb Al-Zoubi and Mohammad Jamous. Treatment of Spinal Cord Injuries Using CD271+ Stem Cells. 5th Pan Arab Spine Congress, Tunis, Tunisia, October, 2007.
Adeeb Al-Zoubi, Mohammed Jamoos, Ziad Al-Zoubi. Magnetic Purification of CD133+ Pluripotent Stem Cells by Nano-Particles for Treatment of Spinal Cord Injuries. 2nd International Conference on Nanotechnology. November 17-20, 2008, Abu-Dhabi, UAE.
Adeeb Al-Zoubi, Mohammed Jamoos, Ziad Al-Zoubi. Utilization of Purified CD133+ Stem Cells for Treatment of Spinal Cord Injuries. 1st Alexandria International Congress on Tissue Engineering. February 13-16, 2009. Alexandria, Egypt.
Adeeb Al-Zoubi, Mohammed Jamoos, Ziad Al-Zoubi. Utilization and Safety Considerations of Purified Autologous CD34+ and CD133+ Stem Cells in Treatment of Spinal Cord Injuries. 7th International Symposium on Experimental Spinal Cord Repair and Regeneration. February 19-21, Brescia, Italy.
Ziad .M. Al Zoubi, Adeeb Al-Zoubi, Mohammed Jamoos: Treatment of Spinal Cord Injuries Using Purified Stem Cells - A Jordanian Experience. 2nd International Association of Neurorestoratology Annual Conference. April 24-26, 2009. Beijing, China.
Adeeb Al-Zoubi. Treatment of Spinal Cord Injuries Using Bone Marrow-Derived CD34+ and CD133+ Stem Cells: A Jordanian Experience. Autologous Stem Cells, Bath, UK, September 20-21, 2009.
Adeeb AlZoubi. Stem Cells: A global Perspective. Proceedings of the Combined Conference of The International Association of Neurorestoratology (IANR IV), Global College of Neuroprotection & Neuroregeneration GCNN 8th), and American Society for Neural Therapy and Repair (ASNTR) conference. April, 2011; Amman, Jordan
Informative Video of our work
https://www.youtube.com/watch?v=F4TTnAf6DG4

Infertility

Al-Zoubi A, Najeeb Layyous. Utilization of Autologous Bone Marrow-Derived Stem Cells in Treatment of Male Infertility, Proceedings of the 5th Joint Annual Conference of The British Royal College of Gynecology and The Jordanian Association of Gynecology, March, 2011, Amman, Jordan. Adeeb Al-Zoubi, Khaldoun Gharaybeh, Ziad AlZoubi, Suleiman Dhabeet, FarahKhalifeh, Feras Twal, Wesam Srour, Sameh Al-Bakheet, Mahasen Zalloum, Samer Abu-Radi, Waleed Dana, and Mohammed El-Khateeb. Intra-Testicular Transplantation of Purified Autologous Stem Cells for Treatment of Chemotherapy-Induced Male Infertility. Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. Abstract # 3038
Informative Video of our work
https://www.youtube.com/watch?v=VVql5r3tJ9E
https://www.youtube.com/watch?v=i6lO_cUYNmo

Diabetes Mellitus - Type 1 and Type 2

Al-Zoubi A, Hazem Haboob, Sameh Al-Bakheet, Marwa Tapponi, Mahasen Zalloum, Samer Abu Radi, Farah Khalifeh, Shahed Sarayrah, Feras AlTwal, Jamil Hermas, Mohammed El-Khateeb, Mark Holterman. Utilization of Purified Autologous Peripheral Blood-Derived Stem Cells, Combined With Immune Modulation by Cord Blood Mesenchymal Stem Cells in Treatment of Type 1 Diabetes Mellitus: A Jordanian Pilot Study. Transfusion. Supplement (2015) 55:2A, CBS1503. Adeeb AlZoubi. Autologous Stem Cells for Beta Cell Regeneration and Treatment of Type 1 Diabetes: The Modified Jordanian Protocol. The 1st. Middle East Wound Care and Diabetic Limb Salvage Conference. Amman, Jordan, May 3-5-2015. Adeeb AlZoubi, Hazem Haboob, Sameh Al-Bakheet, Marwa Tapponi, Mahasen Zalloum, Samer Abu Radi, Farah Khalifeh, Shahed Sarayrah, Feras AlTwal, Jamil Hermas, Jood Hashem, Mohammed El-Khateeb, Mark Holterman. Utilization of Purified Autologous Peripheral Blood-Derived Stem Cells Combined With Immune Modulation by Cord Blood Mesenchymal Stem Cells in Treatment of Type 1 Diabetes Mellitus: A Jordanian Pilot Study. Proceedings of the 13th International Cord Blood Symposium. American Association of Blood Banks (AABB), San Diego, CA, USA, June-11-13-2015
Informative Video of our work
https://www.youtube.com/watch?v=8fIwZZVXWNc
https://www.youtube.com/watch?v=8PZ_Tr4frTY
https://www.youtube.com/watch?v=hlQ-OA3Q1Wk
https://www.youtube.com/watch?v=_IvsMzyuPzI
https://www.youtube.com/watch?v=iCU4x2S--vs
https://www.youtube.com/watch?v=hFuEzaVsfKE

SC in Heart Disease - Cardiomyopathies


https://www.youtube.com/watch?v=NhCuGpxJkkg

Hematological Diseases

Al-Zoubi A, A. A. Al-Abbdi. Magnetic purification of stem cells in treatment of hemoglobinopathies and hematological malignancies: A Jordan University Experience. 2nd International Conference on Nanotechnology. November 17-20, 2008, Abu-Dhabi, UAE

Cancer Immunotherapy

Al-Zoubi A, Mohammad El-Khateeb, Rahaf Al-Zoubi, Shahed AlSarayreh. IL-2 Abrogates MCF7 Cancer Cell-Mediated Inhibition of IFN-g Secretion by T Cells. Submitted for publication. Adeeb M. Al-Zoubi, Rahaf M. Al-Zoubi, Mohammad S. El-Khateeb. MCF7 breast cancer cells inhibit TNF-? production by CD8+ T cells. Personalized Cancer Medicine/Therapies Conference of The American Association for Cancer Research. 2008

IG20 in Cancer

Al-Zoubi A, Efimova EV, Kaithamana S, Martinez O, El-Idrissi MA, Dogan RE, and Prabhakar BS. Contrasting effects of IG20 and its splice isoforms, MADD and DENN-SV, on tumor necrosis factor alpha-induced apoptosis and activation of caspase-8 and -3. J Biol Chem (2001) Dec 14; 276(50): 47202-11. Al-Zoubi AM, Efimova EV, Martinez O, Kaithamana S, Lu SF, Arima T, and Prabhakar BS. Ig20, in Contrast to DENN-SV, (MADD Splice Variants) Suppresses Tumor Cell Proliferation, and Enhances their Susceptibility to Apoptosis and Cancer Drugs. Oncogene (2004) 23, 1076-1087. Adeeb Al-Zoubi, Abdullah Asal, Bellur Prabhakar, Mohammad El-Khatib. hnRNPK is Involved in Regulating Alternative Splicing IG20 mRNA. Manuscript in preparation. Adeeb M. Al-Zoubi, Elena V. Efimova, Shashi Kaithamana, Osvaldo Martinez, Bellur S. Prabhakar: Splice Isoforms of Human IG20: Genomic Organization, Tissue Distribution and Differential Effects on TNF?-Induced Apoptosis. Abstract 770.5; FASEB Annual Meeting of Experimental Biology (2002) 16 (5): p-A1083. Elena V. Efimova, Adeeb M. Al-Zoubi, Shashi Kaithamana, Rukiye E. Dogan, Osvaldo Martinez, Bellur S. Prabhakar: Differential Effects of IG20 and Its Splice Isoform, DENN-SV, on Cell Proliferation and Apoptosis. Abstract770.6; FASEB Annual Meeting of Experimental Biology (2002) 16 (5): p-A1083

Liver Diseases

Al-Zoubi A, and Farah Khalifeh. The effectiveness of stem cell therapies on health-related quality of life and life expectancy in comparison with conventional supportive medical treatment in patients suffering from end-stage liver disease. Stem Cell Research & Therapy Commentary (2013), 4:16.